
产品货号:
Z11930
中文名称:
BCL2A1抗体
英文名称:
Anti-BCL2A1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BCL2A1 Antibody |
指标别名 | BCL2 related protein A1;ACC-1;ACC-2;ACC1;ACC2;BCL2L5;BFL1;GRS;HBPA1;BCL2A1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BCL2A1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Bfl-1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Bfl-1.The immunogen is located within the first 50 amino acids of Bfl-1. |
计算分子量 | 20kDa |
成分 | Bfl-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Bfl-1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Bfl-1 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells and is caused by caspase activation.Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes.One such member is multi-domain antiapoptotic protein Bfl-1,which is overexpressed in stomach and other cancers.Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation.It is upregulated in cisplatin-resistant human bladder tumors,suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells.At least two isoforms of Bfl-1 are known to exist. |
Uniprot ID | Q16548 |
基因名全称 | BCL2-related protein A1 |
蛋白名全称 | BCL2-related protein A1 |
推荐稀释比 | Bfl-1 antibody can be used for the detection of Bfl-1 by Western blot at 1 ~ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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